I'll Use My Best Confidence! is a phrase used to poke fun at Japanese anime-inspired protagonists, much like FOOL! The intentional Engrish and use of cliche might also be a jab at bad dubbing and hammy voice acting. Fraser first created the phrase in the NeverDead episode while comparing past and modern Bryce Boltsman. The phrase has multiple variations and has been used multiple times, sometimes at the top of Fraser's lungs.
Fraser claimed that if he ever did a Kid Icarus game, he'd just be saying "I'll use my best confidence!" nonstop.